Definitions

1. noun

A girl or young woman; a term of endearment.

“She was a sweet sissy, always looking out for her friends.”

2. noun

A person, especially a man, who is considered effeminate or excessively concerned with trivial matters.

“He was called a sissy for crying during the scary movie.”

3. adjective

Excessively concerned with trivial matters; effeminate.

“The sissy in the group was more worried about their hair than the hike.”