Definitions

1. verb

past tense of sclerise: to render or make something hard or hardened, especially by the deposition of a hard substance, such as calcium salts.

“The water in the pool had sclerized over the winter, leaving it unsuitable for swimming.”

2. verb

to convert or replace a membrane or other cell surface component with a hardened substance, such as a glycoprotein.

“The research involved studying the effect of a new treatment on cells that had been sclerized to mimic a disease condition.”