kynurenic

/kɪnjʊˈrɛnɪk/

Definitions

1. adjective

Relating to or derived from kynurenine, a key intermediate in the catabolic pathway of the amino acid tryptophan.

“The kynurenic acid was discovered in a study on tryptophan metabolism.”

2. adjective

Producing or characterized by kynurenic acid, a neuroactive metabolite derived from the breakdown of tryptophan.

“Kynurenic acid is an important neuromodulator in the brain that can have excitatory or inhibitory effects.”

3. noun

A type of acid or compound related to kynurenine, specifically kynurenic acid, which is a byproduct of tryptophan degradation.

“Researchers found that kynurenic has a role in modulating the immune system and in the regulation of neuroinflammation.”

4. noun

A state of being or a condition related to or characterized by the presence of kynurenic acid or its derivatives.

“The kynurenic state is associated with changes in the brain’s neurotransmitter balance and has been linked to neurodegenerative diseases.”

Synonyms

  • neuroactive
  • tryptophanic

Antonyms

  • non-neuroactive
  • tryptophanolytic