Definitions

1. noun

a complex enzyme system consisting of an enzyme and its associated noncatalytic proteins, also known as a multisubunit enzyme.

“The research team studied the structure of the holoenzyme to understand its catalytic function.”

2. noun

an enzyme in its active, fully assembled form, consisting of one or more polypeptide chains and sometimes non-protein groups.

“The enzyme was isolated as a holoenzyme from the cell extract.”