Definitions

1. verb

to cause or make someone feel extremely sad or disappointed

“Her loss of the job would enanguish her for years to come.”

2. noun

the act of causing or making someone feel extremely sad or disappointed

“Her enanguish over the lost relationship left her feeling hopeless.”

3. verb (archaic)

to annihilate or destroy completely

“The powerful army was feared to enanguish the entire city.”