Definitions

1. noun

A congenital defect of the eye or other organ, in which there is a hole or cleft in a structure that should be solid.

“The ophthalmologist specialized in treating colobomas and other congenital eye defects.”

2. noun

A cleft or gap in an organ or tissue, especially one that is present at birth.

“The baby was born with a coloboma in the iris of her eye.”